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WUHAN DONG KANG YUAN TECHNOLOGY CO., LTD.

53123-88-9, Rapamycin, Rapamycin API manufacturer / supplier in China, offering Rapamycin API Product Technical Parameters of Basic Uses Synthesis Testing Standards, White Powder Granule Potassium Chloride (KCL) for Oil Drilling, High Quality Food Ingredient Nutrition Sodium Propionate and so on.

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Supplier Homepage Product Pharmaceutical raw materials Rapamycin API Product Technical Parameters of Basic Uses Synthesis Testing Standards

Rapamycin API Product Technical Parameters of Basic Uses Synthesis Testing Standards

FOB Price: Get Latest Price
Min. Order: 1 g
Port: Shanghai, China
Production Capacity: 20tons/Year
Payment Terms: T/T, D/P, Western Union, Money Gram
Basic Info
  • Model NO.: Pharmaceutical grade
  • Customized: Customized
  • Suitable for: Adult
  • Purity: >99%
  • Transport Package: 1 G Aluminum Foil Bag
  • Origin: China
  • Powder: Yes
  • Certification: USP, BP
  • State: Solid
  • Trademark: DKY
  • Specification: Pharmaceutical raw materials
  • HS Code: 2851686515
Product Description
Product Name: Rapamycin
Synonyms: AY 22989;23,27-EPOXY-3H-PYRIDO(2,1-C)(1,4)OXAAZACYCLOHENTRIACONTINE;NSC-226080;RAPA;RAPAMUNE;RAPAMYCIN;RAPAMYCIN, STREPTOMYCES HYGROSCOPICUS;RPM
CAS: 53123-88-9
MF: C51H79NO13
MW: 914.18
EINECS: 262-640-9

Uses Used as immunosuppressant.
This information is edited by ChemicalBook Xiao Nan.
Chemical Properties White to Off-White Solid
Usage A specific mTOR inhibitor with an IC50 of 0.1 nM.
Usage antidepressant
Usage immunosuppressant, antineoplastic; rapamycin
Usage Rapamycin is a triene macrolide discovered in 1995 as a metabolite of Streptomyces hygroscopicus found in a soil obtained on Rapi Nui (Easter Island). Rapamycin displayed potent and selective antifungal activity, notably against Candida albicans. Interest in the metabolite waned until the structural relationship to the potent immunosuppressant fujimycin (Antibiotic FK506) was recognised in the mid-1980s. This recognition led to the re-discovery of rapamycin as a highly selective antitumour and immunosuppressant. Rapamycin inhibits the activity of the protein, mTOR (mammalian target of rapamycin) which functions in a signalling pathway to promote tumour growth. Rapamycin binds to a receptor protein (FKBP12). The rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signalling pathway.
Usage DDP-4 inhibitor type 2 diabetes therapeutic
Usage Rapamycin is a triene macrolide discovered in 1974 as a metabolite of Streptomyces hygroscopicus found in a soil obtained on Rapa Nui (Easter Island). Rapamycin displayed potent and selective antifungal activity, notably against Candida albicans. Interest in the metabolite waned until the structural relationship to the potent immunosuppressant fujimycin (Antibiotic FK506) was recognised in the mid-1980s. This recognition led to the re-discovery of rapamycin as a highly selective antitumor and immunosuppressant. Rapamycin inhibits the activity of the protein, mTOR (mammalian target of rapamycin) which functions in a signalling pathway to promote tumor growth. Rapamycin binds to a receptor protein (FKBP12). The rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signalling pathway.
Usage Labelled Rapamycin. A triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa?Nui. Used as an immunosuppressant; antirestenotic. This compound contains aproximately 2% d0.;Labeled Sir



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